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Applications of Current Density Imaging - Page 1 [<<][ < ][ > ][>>]

CDI has been used in the following biomedical studies:

Transcranial Electro-stimulation (TCES) (University of Toronto - Canada)

In this series of experiments, CDI was used to investigate electrical current pathways through the head of a rabbit. Knowledge of these current pathways was used to better understand the mechanisms underlying the analgesic effects associated with the TCES technique. [Mike Joy, Val Lebedev, Joe Gati & David Thompson]

Spreading Depression in a Rodent Cortex (University of Toronto - Canada)

In this series of experiments, current density measurements were made in the brain of a rat when a spreading depression was induced on one hemisphere. Measurable differences in the two hemispheres were attributed to tissue conductivity changes that accompany a widespread depolarization of excitable cells. [Richard Yoon, Han Kwan & Mike Joy]

EEG Source Localization (University of Toronto - Canada)

A highly accurate solution to the EEG source localization forward problem was demonstrated in a gel phantom. In this technique, assumptions and estimates of tissue conductivities (i.e. the head model) are replaced by actual measurements of the lead fields using CDI. These initial results are encouraging and should lead towards a more accurate solution to the EEG source localization inverse problem. [Nanping Zhang, Maggie Kusano, Leili Torab & Mike Joy]

Surface-stimulating Electrode Studies (University of Toronto - Canada & Aalborg University - Denmark)

Researchers and designers of electrostimulation devices (e.g. TENS, NMES, etc.) would like to know more accurately where current flows inside tissue as it passes between the electrodes. As an initial investigation, CDI was used to measure current density distributions a few millimeters beneath a surface electrode placed on a homogenous gel phantom. The results compare well with finite element solutions. The next step is to repeat the experiments on a more complicated phantom that contains more features of real tissue. Future plans for this project include in-vivo experiments. [Andrei Patriciu, Tim DeMonte & Mike Joy]